Glucagon regulates hepatic lipid metabolism via camp and insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis

HIGHLIGHTS

• who: Hai Wang from the University of Nebraska-Lincoln, Lincoln, NE, USA have published the research: Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis, in the Journal: Scientific Reports Scientific Reports
• how: At a glance this result is at odds with the hyperactivation of HMG-CoA reductase and HMG-CoA synthase (Supplementary Fig S2B).

SUMMARY

After determining the mRNA levels of CREBH and Insig-2a in the livers of the mice by quantitative real-time PCR, the authors found . . .

 



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