Glucocorticoid induced group 2 innate lymphoid cell overactivation exacerbates experimental colitis

HIGHLIGHTS

  • who: Bingcheng Feng from the University of Zurich, Switzerland have published the Article: Glucocorticoid induced group 2 innate lymphoid cell overactivation exacerbates experimental colitis, in the Journal: (JOURNAL)
  • what: The study demonstrates that abnormal stimulation of ILC2 induced by HPA axis overactivation results in oversecretion of type II cytokines, leading to inflammation expansion in colitis.
  • how: These results indicated that ILC2 secreted a major part of type II cytokines and their function was strengthened after WRS.

SUMMARY

    Inflammatory bowel diseases, including ulcerative colitis (UC) and Crohn`s disease (CD . . .

     

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