Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine

HIGHLIGHTS

  • who: Pier-Vincenzo Piazza from the UMR , CNRS, Physiopathologie des Maladies du Système Nerveux Central, "Gene Regulation and Adaptive Behaviors" Group, Paris, France Department, Columbia University, York, NY, USA have published the research: Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine, in the Journal: (JOURNAL)
  • what: This experiment shows that GR positively controls the reactivity to glutamate of a subset of NAc medium spiny neurons. The authors aimed at dissecting the modulatory role of GR within the meso-cortico-limbic dopamine system, on responses to amphetamine and food . . .

     

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