HIGHLIGHTS
SUMMARY
Most solutions employed for cells and tissues are ‘extracellular-type` isotonic solutions (e_g, histidine-tryptophan-ketoglutarate (HTK), gluconate-lactobionate-dextran (Unisol)-low potassium (ULK)), with a plasma-like formulation of ions that mimics the normal extracellular environment of cells. Unisol-high-potassium (UHK), in contrast, is an ‘intracellulartype` hypertonic solution (e_g, University of Wisconsin (UW) solution) that mimics high intracellular potassium and low sodium concentrations, which is designed to restrict the passive exchange of water and ions during hypothermic exposure when cell membrane pumps are inhibited. This study aimed to assess the potency of . . .
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