HIGHLIGHTS
- who: Sienna R. Li from the Research complied with all relevant ethical regulationsHuman PKD kidney tissue (nephrectomy) was obtained with informed consent under a human subjects protocol approved by the University of Washington Institutional Review Board. No compensation was provided to study participants. have published the paper: Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease, in the Journal: (JOURNAL) of 30/Oct/2022
- what: The authors show that subjecting organoids to fluid shear stress in a PKD-on-a-chip microphysiological system promotes cyst expansion via an absorptive . . .
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