HIGHLIGHTS
- who: Qiao Zeng from the (UNIVERSITY) have published the Article: Glutamate dehydrogenase hyperinsulinism: mechanisms, diagnosis, and treatment, in the Journal: (JOURNAL)
- what: The aim of this review is to summarize the genetic mechanisms diagnosis and treatment progress of GDH-HI. This study showed for the first time that GDH-induced hypoglycemia was associated with impaired function of u03b1 cells .
- how: Their results showed that mitochondria guanosine triphosphate (mtGTP) in islet u03b2 cells was insensitive inhibiting the secretion of glucagon by u03b1 cells and leading to glucagon deficiency.
SUMMARY
Insulin . . .
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