Glutamatergic and gabaergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes

HIGHLIGHTS

• who: Lihua Qin from the Shandong University, China have published the Article: Glutamatergic and GABAergic neurons in the preoptic area of the hypothalamus play key roles in menopausal hot flashes, in the Journal: (JOURNAL)
• what: The experiments showed that the number of glutamatergic and GABAergic neurons in the POA of ovariectomized rats significantly decreased and increased, respectively, and that estrogen supplementation significantly corrected this abnormality, suggesting that estrogen can promote glutamatergic neurons and inhibit GABAergic neurons. The results of this experiment showed that ovariectomized rats had no estrous cycle and always showed the diestrous stage . . .
  

   

  

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