Glutamine availability controls bcr/abl protein expression and functional phenotype of chronic myeloid leukemia cells endowed with stem/progenitor cell potential

HIGHLIGHTS

  • who: Martina Poteti and colleagues from the Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale GBMorgagni, Medical School, Brookline Boston, MA, USA have published the Article: Glutamine Availability Controls BCR/Abl Protein Expression and Functional Phenotype of Chronic Myeloid Leukemia Cells Endowed with Stem/Progenitor Cell Potential, in the Journal: Cancers 2021, 13, x FOR PEER REVIEW of 15/07/2021
  • what: On this basis, the authors propose glutamine availability as a feature of the SCN zone hosting TKi-resistant MRD of CML. This study showed that glutamine is a critical regulator . . .

     

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