HIGHLIGHTS
- who: Tengfang Gong from the University of Salford, United Kingdom have published the Article: Glutamine metabolism in cancers: Targeting the oxidative homeostasis, in the Journal: (JOURNAL)
- what: Interestingly, this study has also shown that the activated Wnt/b-catenin pathway via its agonist SKL2001 could upregulate the mRNA and protein levels of GLS1, and then promote Gln metabolism, which means that activated Wnt/b-catenin pathway could promote GLS expression with positive feedback .
- how: The result showed that GSH and GSSG levels were markedly reduced in the Gln-depleted group which confirms the . . .
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