HIGHLIGHTS
SUMMARY
The activation of free_radical oxidation can provoke the transformation of normal cells into tumors. To neurotransmitters, which are capable of becoming sources of free_radical compounds and activated microglia, continuously producing active forms of oxygen, the level of antioxidant protection systems in the brain is low. An important role in the protection of cells against free_radical oxidation belongs to indicators characterizing glutathione defense adequacy. Glutathione is an intracellular antioxidant, acting as a "trap" for free_radicals as well as being a co-substrate in peroxide detoxification reactions catalyzed by glutathione peroxidase and glutathione transferase. In this . . .
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