HIGHLIGHTS
- who: Jose J., Reina and Javier, Rojo from the Institut CSIC, Univesity of Seville, Seville, Spain Autu00f3noma University have published the research work: Glycodendritic structures: tools to interact with DC-SIGN, in the Journal: (JOURNAL)
- what: The experiment showed that BH30sucMan was able to selectively inhibit direct DC-SIGN-mediated Ebola infection in an efficient dose-dependent manner (IC50 337 nM).
- how: The tetra- and multivalent systems were tested in_vitro using an infection model based on pseudotyped viral particles with the Ebola virus envelope glycoprotein GP1. The well-defined polyvalent glycoprotein assemblies presenting . . .
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