Glycogen storage disease phenotypes accompanying the perturbation of the methionine cycle in ndrg3-deficient mouse livers

HIGHLIGHTS

  • who: Hyun Ahm Sohn et al. from the Department of Biological Sciences, Advanced Institute of Science and Technology, KoreaDepartment of Functional Genomics, KRIBB School of Bioscience, University of Science and Technology have published the research work: Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers, in the Journal: Cells 2022, 1536 of 29/04/2022
  • what: NDRG3 depletion in liver results in the manifestation of GSD phenotypes in mice due to impaired hepatic glucose homeostasis associated with the suppression of glycogenolysis and gluconeogenesis.
  • how: Similar observations . . .

     

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