Glycosaminoglycan signatures in body fluids of mucopolysaccharidosis type ii mouse model under long-term enzyme replacement therapy

HIGHLIGHTS

  • who: Francesca Maccari from the (UNIVERSITY) have published the research: Glycosaminoglycan signatures in body fluids of mucopolysaccharidosis type II mouse model under long-term enzyme replacement therapy, in the Journal: (JOURNAL)
  • what: The authors report the characterization of plasma and urine GAGs in Ids knock-out (Ids-ko) compared to (WT) mice and their changes along a 24-week follow-up with and without ERT. Among them, the authors report in Fig 3a, b the percentage of disaccharide disulfated in position 2 of uronic acid and 4 of GalNAc (disaccharide B or 2,4dis).
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