Glycosylated modification of muc1 maybe a new target to promote drug sensitivity and efficacy for breast cancer chemotherapy

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  • who: Xiaomin Xi from the Tumor xenograft model All animal experiments were approved by institutional animal care and used committees of China Agricultural UniversityFemale BALB/c Nude mice were purchased from SPF Biotechnology Co [, ]. Ltd (Charles River, Beijing, China), and raised in the SPF animal center of China Agricultural University. The , WT and , KO at a concentration of , × , cells/, μl mixture (PBS:Matrigel=1:1, Gibco, Invitrogen, Carlsbad, CA, USA) each mice were inoculated subcutaneously on the right armpit of nude mice aged , weeks. After , week, the nude mice with successful xenogeneic tumor transplantation were randomly divided . . .

     

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