HIGHLIGHTS
- who: Juan Liu from the Institut Medical University, Shanghai, China have published the article: Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity, in the Journal: (JOURNAL) of January/31,/2023
- what: The authors report that Extl1 (Exostosin like glycosyltransferase 1), significantly upregulated by CCR7L, acts as a key activator of CCR7-triggered DC migration. The authors demonstrate that the Extl1 plays an important role in promoting CCR7-triggered DC migration to restrain infection and autoimmunity in an HSPG-dependent manner. Together, the authors demonstrate that Extl1 is required for host . . .
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