Golgi outpost synthesis impaired by toxic polyglutamine proteins contributes to dendritic pathology in neurons

HIGHLIGHTS

• who: Chang Geon Chung from the of Brain and Cognitive Sciences, DGIST, Daegu, Republic of Korea Hee University have published the research work: Golgi Outpost Synthesis Impaired by Toxic Polyglutamine Proteins Contributes to Dendritic Pathology in Neurons, in the Journal: (JOURNAL) of July/11,/2017
• what: For this analysis, the authors compared dendrite images of C4 da neurons expressing 78Q (78Q OE; n=6) and wild-type C4 da neuron controls (w ; n=6; Figures 1A and S1A-S1G). The authors propose a mechanistic model that links toxic nuclear polyQ proteins to the impaired elongation . . .
  

   

  

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