HIGHLIGHTS
SUMMARY
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death and the second leading cause of cancer death worldwide. The expression of GPBAR1 and its clinical significance, especially the prognostic significance in HCC, are still unknown. The authors investigated the expression of GPBAR1 in HCC tissues and tumor-adjacent tissues. The authors evaluated the clinical significance of GPBAR1 in HCC by analyzing its correlation with clinicopathological factors, overall survival (OS) rate, and asynchronous metastases to the liver, lung, and bone. Correlation between asynchronous metastasis and GPBAR1 Asynchronous metastases of HCC, including intrahepatic . . .

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