HIGHLIGHTS
- who: Ying Wang from the Institute University of, Bristol , TD, UK have published the Article: GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- how: Similar results were obtained using siRNA against INF2 (Supplementary Fig 3A B).
SUMMARY
Filamentous actin structures were discovered in the nucleus when cells undergo serum stimulation, T-cell activation, DNA damage, or mitotic cell division3-5. Heterotrimeric G proteins are key components of transmembrane signal_transduction via G-protein-coupled receptors (GPCRs), controlling a plethora of vital physiological . . .
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