Gpr68 limits the severity of chemical-induced oral epithelial dysplasia

HIGHLIGHTS

  • who: David Shore from the School of Pharmacy, Huntington, WV, USA Marshall University have published the research: GPR68 limits the severity of chemical-induced oral epithelial dysplasia, in the Journal: Scientific Reports Scientific Reports
  • future: Given the link to Treg elevation in clinical cases future studies are necessary to determine how the tumor microenvironment including GPR68 expression regulates their accumulation and function.

SUMMARY

    To determine if GPR68 regulates angiogenesis in_vivo, tongue sections were stained for CD31 by immunohistochemistry. GPR68 alters the frequency of splenic regulatory T_cells (Tregs) following oral 4NQO treat . . .

     

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