Grhl2-controlled gene expression networks in luminal breast cancer

HIGHLIGHTS

  • who: Zi Wang from the (UNIVERSITY) have published the paper: GRHL2-controlled gene expression networks in luminal breast cancer, in the Journal: (JOURNAL)
  • what: The authors explore genome wide binding sites conserved in three ERu237a/GRHL2 positive cell lines by Interaction with the ERu237a/FOXA1/GATA3 complex is observed however only for a minor fraction of conserved peaks. The authors determine genome wide transcriptional dynamics in response to loss of by nascent RNA using an MCF7 conditional knockout model. For genes showing sustained up- or downregulation in response to GRHL2 deletion, the authors explore correlations . . .

     

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