Grk2 regulates glp-1r-mediated early phase insulin secretion in vivo

HIGHLIGHTS

• who: Alba C. Arcones from the Experiments were performed using young (~ , months old) male C BL/, J (WT) mice and mice made hemizygous for , (GRK2+/-, [33]) maintained on the C BL/, J backgroundAnimals were bred at a room temperature of , ± , °C on a, :, light-dark cycle (lights on at, :, am) with a relative humidity of , ±, % and under pathogen-free conditions in the animal facility of the Centro de Biologia Molecular Severo Ochoa with free access to food and water. Mice were euthanized using , or cervical dislocation, and body and pancreas weight was measured. Before group assignation, animals . . .
  

   

  

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