Growth‐dependent heterogeneity in the dna damage response in escherichia coli

HIGHLIGHTS

  • who: Subject Categories DNA Replication and collaborators from the (UNIVERSITY) have published the research: Growthu2010dependent heterogeneity in the DNA damage response in Escherichia coli, in the Journal: (JOURNAL)
  • what: In the rest of the analysis, the authors focus on the fraction of cells whose fluorescence intensity is above 5 a.u./area. The authors show that heterogeneity in the levels of SOS expression induced by chronic sub-lethal DNA-damage exhibits strong growth-dependence.
  • how: This result is unexpected given the positive correlation of SOS levels with growth rates for the main population . . .

     

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