Growth and differentiation factor is secreted by skeletal muscle during exercise and promotes lipolysis in humans

HIGHLIGHTS

  • who: Claire Laurens and collaborators from the Institut University of, Dublin, Ireland Inserm, Clinical Investigation Center CIC, Toulouse, France. have published the research work: Growth and differentiation factor is secreted by skeletal muscle during exercise and promotes lipolysis in humans, in the Journal: (JOURNAL)
  • what: This study aimed at identifying exercise-regulated myokines also known as exerkines able to promote lipolysis. The authors show that conditioned media (CM) from exercised human myotubes activate lipolysis in human adipocytes in_vitro. Even more remarkable, the authors demonstrate that blocking GDF15 with a neutralizing IgG antibody of hGDF15 completely . . .

     

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