Growth differentiation factor 7 prevents sepsis-induced acute lung injury in mice

HIGHLIGHTS

• who: Ping Dong and collaborators from the Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China have published the Article: Growth Differentiation Factor 7 Prevents Sepsis-Induced Acute Lung Injury in Mice, in the Journal: Evidence-Based Complementary and Alternative Medicine of 22/Dec/2022
• what: The authors provide in_vivo and in_vitro evidence that GDF7 prevents LPS-induced ALI through depressing infammatory response and oxidative stress. The authors demonstrated that STING downregulation was required for AMPK activation by rmGDF7 and that STING KO abolished rmGDF7-mediated additional inhibitions against sepsis-induced infammation and oxidative stress . . .
  

   

  

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