Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences (âˁ⠎)

HIGHLIGHTS

  • who: Elliot L. Chaikof from the Departments Emory University have published the Article: Growth-related Responses in Arterial Smooth Muscle Cells Are Arrested by Thrombin Receptor Antisense Sequences (âˁ⠎), in the Journal: (JOURNAL) of January/10,/1995
  • what: The authors report that specific reduction of thrombin receptor-mediated events is possible using a receptor-specific antisense DNA sequence. The authors report that when thrombin receptor expression is inhibited using an antisense sequence specific for nucleotides 4-20 of the rat thrombin receptor, there is a significant reduction of smooth muscle cell mitogenesis, not only in response . . .

     

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