Gtp energy dependence of endocytosis and autophagy in the aging brain and alzheimer’s disease

HIGHLIGHTS

• who: Ricardo A. Santana Martu00ednez from the Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA have published the article: GTP energy dependence of endocytosis and autophagy in the aging brain and Alzheimeru2019s disease, in the Journal: (JOURNAL)
• what: The authors propose that the redox state of cells and possibly a systemic redox shift are an essential driver of aging .
• future: And future studies A surprising array of specific GTPase control macroautophagy (mitophagy) microautophagy chaperone-mediated autophagy (CMA) and endocytosis and vesicle and mitochondrial trafficking. Age-related changes in GTP levels . . .
  

   

  

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