Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments

HIGHLIGHTS

  • who: Xiaohua Zhang from the Male C BL/, mice between , and , weeks old were purchased from the CHENGDU DOSSY EXPERIMENTAL ANIMALS CO, LTD. All mice were housed under the same conditions and treated similarly. For the experiment presented in Figure, mice were randomly divided into , groups (n=6, per group), and inoculated with PRV (, u00d7 u00ad, u00adTCID50) or mock (same volume of DMEM) for , h by intramuscular injection. The liver, lung, heart, kidney, spleen, and brain tissues were collected for further analysis. The animal experiments with mice were approved by the Institutional Animal Care and Use Committee . . .

     

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