Guanylate-binding protein 5 licenses caspase-11 for gasdermin-d mediated host resistance to brucella abortus infection

HIGHLIGHTS

• who: Daiane M. Cerqueira and collaborators from the Departamento Bioquu0131u0301mica Imunologia, Instituto Ciu00eancias Biolou0301gicas, Universidade Federal Salvador, Bahia, Brazil have published the paper: Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection, in the Journal: (JOURNAL) of November/27,/2018
• what: The authors demonstrate that B. abortus triggers non-canonical inflammasome activation dependent on caspase-11 and gasdermin-D (GSDMD). Interestingly the authors determine that B. abortus is able to trigger pyroptosis leading to pore formation and cell death and this process is dependent on caspase-11 . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.