Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on l-type calcium channels

HIGHLIGHTS

  • who: Barbora Waclawikovu00e1 and collaborators from the University of Groningen, Groningen, the Netherlands, Department of Molecular Neurobiology, Groningen have published the paper: Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on L-type calcium channels, in the Journal: (JOURNAL) of January/22,/2021
  • what: The authors show that a wide variety of can metabolize the dietary supplement and antidepressant 5-hydroxytryptophan (5-HTP) to (5-HI) via the tryptophanase (TnaA) enzyme. The authors describe how 5-HTP is metabolized by gut bacteria. The authors focused on the colon . . .

     

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