Gut colonisation with multidrug-resistant klebsiella pneumoniae worsens pseudomonas aeruginosa lung infection

HIGHLIGHTS

  • who: Ru00e9mi Le Guern from the (UNIVERSITY) have published the research work: Gut colonisation with multidrug-resistant Klebsiella pneumoniae worsens Pseudomonas aeruginosa lung infection, in the Journal: (JOURNAL) of 18/Dec/2021
  • what: The authors show that in a murine model, CPE gut colonisation alters the lung immune_response to P. aeruginosa infection and worsens outcomes by modulating the gut-lung axis differently from antibiotic-induced dysbiosis. In the model , colonisation was possible following FMT because a diverse ecosystem was provided, confirming that Muribaculaceae are not able to colonise the gut when they are given individually . . .

     

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