Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation

HIGHLIGHTS

  • who: Aurélien Trompette from the (UNIVERSITY) have published the paper: Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation, in the Journal: (JOURNAL) of 25/04/2022
  • what: Their impact upon non-immune cells, on the other hand, is less well understood, with most research focusing on local effects in the gastrointestinal tract36-40. Of note, previous data from the laboratory using this model demonstrated that without addition of HDM allergens, occlusion with a saline control patch does not lead to overt skin inflammation, or skin barrier . . .

     

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