Gut-on-a-chip for exploring the transport mechanism of hg(ii)

HIGHLIGHTS

  • who: Li Wang from the (UNIVERSITY) have published the paper: Gut-on-a-chip for exploring the transport mechanism of Hg(II), in the Journal: (JOURNAL)
  • what: The decrease in ZO-1 protein expression was the main reason for the decrease in TEER.
  • how: To determine whether fluid flow and mechanical strain alter cytodifferentiation the authors analyzed the catalytic activity of alkaline phosphatase (AKP) in Caco-2 cells. These results showed that when mechanical stimulation increased the absorption of Hg(II) by intestinal epithelial_cells increased and Piezo1 and DMT1 also showed a positive . . .

     

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