Gwas of epigenetic aging rates in blood reveals a critical role for tert

HIGHLIGHTS

  • who: Ake T. Lu from the (UNIVERSITY) have published the research: GWAS of epigenetic aging rates in blood reveals a critical role for TERT, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors examine two widely used measures of epigenetic age acceleration: (a) intrinsic epigenetic age acceleration (IEAA), based on 353 CpGs described by Horvath2, which is independent of age-related changes in blood cell composition, and_(b) extrinsic epigenetic age acceleration (EEAA), an enhanced version of that based on 71 CpGs described by Hannum which upweights the contribution of blood cell count measures1 . . .

     

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