Gwas of peptic ulcer disease implicates helicobacter pylori infection, other gastrointestinal disorders and depression

HIGHLIGHTS

  • who: Yeda Wu from the Institute The University Cambridge, Cambridge, UK have published the Article: GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Given increasing evidence for the importance of bidirectional signaling between the brain and the gut25-28, possibly contributing to observational associations between depression and PUD29, GORD30, IBS31, and IBD32, the authors explore the potential causal relationships between major depression (MD) and the four disorders using Mendelian randomization (MR). The authors show genetic similarity across PUD, GORD, and IBS . . .

     

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