H1153y-kcnh2 mutation identified in a sudden arrhythmic death syndrome case alters channel gating

HIGHLIGHTS

• who: Audrey Farrugia and colleagues from the Institut Légale, (FMTS), Université, Rue Humann, France have published the article: H1153Y-KCNH2 Mutation Identified in a Sudden Arrhythmic Death Syndrome Case Alters Channel Gating, in the Journal: (JOURNAL) of 27/07/2021
• what: In the present work, the proportion of the fastest kinetic component of deactivation or tail current was significantly reduced for the H1153Y variant, and the authors observed an altered cooperative mechanism in the activation process of the channel compared to the WT (p and amp;lt; 0.005). To conclude, this study characterized . . .
  

   

  

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