H2a.z deposition by swr1c involves multiple atp-dependent steps

HIGHLIGHTS

• who: Jiayi Fan from the (UNIVERSITY) have published the research work: H2A.Z deposition by SWR1C involves multiple ATP-dependent steps, in the Journal: (JOURNAL) of 21/07/2022
• what: Using crosslinking, the authors show that SWR1C does not change the path of DNA on the histone octamer surface during its ATPdependent deposition of H2A.Z. Instead, single-molecule experiments show that dimer exchange occurs through three distinct phases, two of which are sensitive to ATP concentration.
• how: The smFRET data was collected at a surface power density of 1.9 mW/cm2 . . .
  

   

  

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