H3k27 tri-demethylase jmjd3 inhibits macrophage apoptosis by promoting adora2a in lipopolysaccharide-induced acute lung injury

HIGHLIGHTS

• who: Yizhuo Gao from the Therefore, we chose male C BL/6j mice (aged, weeks, weight, g) (HFK Bioscience CoLtd, Beijing, China) and raised the mice in a pathogen-free environment (Shengjing Hospital of the China Medical University, Centre laboratory) under a, h/12-h dark/light cycle and provided ad libitum access to food and water. ALI model for mice was built by a method of intraperitoneal LPS (Escherichia coli, :, Sigma, USA). LPS (Escherichia coli, :, Sigma, USA) was dissolved in PBS to achieve a final concentration of , mg/ ml., ., mg/kg of this LPS solution was . . .
  

   

  

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