HIGHLIGHTS
- who: Serena Ammendola et al. from the Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy have published the research work: H3K27me3 Immunohistochemical Loss Predicts Lower Response to Neo-Adjuvant Chemo-Radiotherapy in Rectal Carcinoma, in the Journal: Biomedicines 2022, 2042 of /2022/
- what: 15.7% of patients managed with this approach have local regrowth within two years , likely because imaging overestimates tumor regression . This study demonstrated that the immunohistochemical loss of H3K27me3 before treatment is associated with significantly lower pathological response (measured using ypTNM stage and Dworak TRG) of . . .
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