Hal-2 promotes homologous pairing during caenorhabditis elegans meiosis by antagonizing inhibitory effects of synaptonemal complex precursors

HIGHLIGHTS

  • who: HAL- and colleagues from the Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, California, United States of America, Institute for Integrated have published the research work: HAL-2 Promotes Homologous Pairing during Caenorhabditis elegans Meiosis by Antagonizing Inhibitory Effects of Synaptonemal Complex Precursors, in the Journal: (JOURNAL) of April/25,/2012
  • what: The authors propose that HAL-2 functions to shepherd SYP proteins prior to licensing of SC assembly preventing untimely interactions between SC precursors and chromosomes and allowing sufficient accumulation of precursors for rapid cooperative assembly upon homology verification . . .

     

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