Haploinsufficiency of dmxl2 encoding synaptic neurons in mouse

HIGHLIGHTS

• who: Brooke Tata and collaborators from the Diabétologie Pédiatrique et Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Hôpital Robert Debré, France have published the research: Haploinsufficiency of Dmxl2 Encoding Synaptic Neurons in Mouse, in the Journal: (JOURNAL) of September/23,/2014
• what: This study shows that low levels of DMXL2 expression cause a complex neurological phenotype with abnormal glucose metabolism and gonadotropic axis deficiency due to a loss of GnRH neurons.
• how: The authors recently decided to investigate these common mechanisms further by characterizing the . . .
  

   

  

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