HIGHLIGHTS
SUMMARY
Recent evidence suggests that additional common variants beyond the lead GWAS single nucleotide polymorphisms (SNPs) contribute to disease risk (Gusev et_al, 2013; Corradin et_al, 2014; Gusev et_al, 2014; Corradin et_al, 2016; Boyle et_al, 2017). Combinations of genetic polymorphisms affecting various components in this process may thus alter gene_expression and contribute to disease risk. Capture Hi-C, a highthroughput method to identify chromatin interactions in large genomic regions, has been used to determine high-resolution 3D genome structures at some disease-associated loci (Dryden et_al, 2014; Jäger et_al, 2015). To investigate the role of . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.