Haplotyping pharmacogenes using tla combined with illumina or nanopore sequencing

HIGHLIGHTS

  • who: Laurentijn Tilleman from the LaboratoryGhent University have published the paper: Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing, in the Journal: Scientific Reports Scientific Reports
  • what: This study sequenced TLA libraries of four different pharmacogenes, CYP2D6, CYP2C19, CYP1A2, and BRCA1, using Illumina and Nanopore sequencing technologies.

SUMMARY

    As CYP2D6, CYP2D7 and the sequences upstream and downstream of these genes are highly similar to each other, not many positions are available to design viewpoints for that pharmacogene. The results for BRCA1 cannot be compared directly with the previously generated . . .

     

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