Harmonizr enables data harmonization across independent proteomic datasets with appropriate handling of missing values

HIGHLIGHTS

• who: Hannah Vou00df from the Chemistry and Laboratory University Medical Center Hamburg-Eppendorf, Hamburg, Germany have published the research: HarmonizR enables data harmonization across independent proteomic datasets with appropriate handling of missing values, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: In the following, the authors show that HarmonizR-based integration of independent proteomic datasets, acquired from different tissue types, by different quantification strategies and instrumental setups is possible. The study reveals that parallelizing the execution of ComBat and limma is sufficient to improve the performance of the program by a factor 2 (limma)/ factor . . .
  

   

  

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