Harnessing epithelial-mesenchymal plasticity to boost cancer immunotherapy

HIGHLIGHTS

  • who: Yuanzhuo Gu from the (UNIVERSITY) have published the Article: Harnessing epithelial-mesenchymal plasticity to boost cancer immunotherapy, in the Journal: (JOURNAL) of 24/02/2023
  • what: Thereafter, the authors discuss how EMP is linked to ICB resistance via tumor-intrinsic and tumor-extrinsic mechanisms. In the forthcoming sections, the authors provide a critical overview of studies reporting (causal) links between EMP states as determinants for the efficiency of the ICB therapy response.
  • future: In future studies single-cell analysis of tumors treated with ICBs will help the authors to better understand how . . .

     

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