Hassall’s corpuscles with cellular-senescence features maintain ifn α production through neutrophils and pdc activation in the thymus

HIGHLIGHTS

• who: Jianwei Wang et al. from the Department of Immunology and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan have published the research: Hassall’s corpuscles with cellular-senescence features maintain IFN α production through neutrophils and pDC activation in the thymus, in the Journal: (JOURNAL)
• how: These results indicated that a rare fraction of mTECs expressing a high level of Asprv1 (SASPhigh) characterized HC-mTECs that are highly matured and exhibit features of cornification but at the same time they showed lower expression of several functional molecules expressed in the majority of mature . . .
  

   

  

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