Hb-gam (pleiotrophin) reverses inhibition of neural regeneration by the cns extracellular matrix

HIGHLIGHTS

• who: Mikhail Paveliev from the Neuroscience Center, University of Helsinki, Finland have published the article: HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix, in the Journal: Scientific Reports Scientific Reports
• what: Quantification of the experiment showed significant regeneration based on the density of the dendritic tuft (Fig 6k) and on the number of apical dendrites normalized to the corresponding distant area of the cortex (Fig 6l). The authors show that HB-GAM is a potent inhibitor of PTPσ​binding to CS chains.
• how: Altogether the data showed that . . .
  

   

  

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