HIGHLIGHTS
- who: Doudou Tan from the Shanghai Institute of have published the research work: HBO1 catalyzes lysine benzoylation in mammalian cells, in the Journal: (JOURNAL) of November/18,/2022
- what: The authors report the global profiling of benzoylome in mammalian cells, identifying 1747 Kbz sites.
- how: The authors hypothesized that some KATs may have benzoyltransferase activity as well. The kinetic analysis results showed that the Kcat values of HAT1 and HBO1 in the Kbz reaction were close to those for Kac. The results showed that its homolog GCN5 could not catalyze the Kbz reaction . . .
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