Hboc-301 in porcine kidney normothermic machine perfusion and the effect of vitamin c on methemoglobin formation

HIGHLIGHTS

  • who: Eileen Edgworth and collaborators from the Department of Anesthesiology, Medical Faculty, University Hospital RWTH Aachen, Aachen, Germany have published the research work: HBOC-301 in Porcine Kidney Normothermic Machine Perfusion and the Effect of Vitamin C on Methemoglobin Formation, in the Journal: Antioxidants 2022, 11, x FOR PEER REVIEW Antioxidants 2022, 11, x FOR PEER REVIEW of /2022/
  • what: This study demonstrated that HBOC-301 is inferior to pRBCs in the porcine kidney NMP model independent of additional VitC administration. Oxidative stress and fragmentation of the hemoglobin polymers could be detected as a possible . . .

     

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