Hcn-channel-dependent hyperexcitability of the layer v pyramidal neurons in il-mpfc contributes to fentanyl-induced hyperalgesia in male rats

HIGHLIGHTS

• who: Posted Date October and collaborators from the Huazhong University of Science and Technology Tongji Medical College have published the research work: HCN-channel-dependent hyperexcitability of the layer V pyramidal neurons in IL-mPFC contributes to fentanyl-induced hyperalgesia in male rats, in the Journal: (JOURNAL)
• what: The authors reported specific excitatory changes of pyramidal neurons in the IL-mPFC Layer V and examine the molecular mechanisms by which these neurons may be involved in OIH regulation.
• how: The results indicated that optical activation of IL-mPFC glutamatergic neurons in control rats . . .
  

   

  

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