HIGHLIGHTS
- who: Hao Cai from the Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc, DNA Way, South San Francisco, California, USA have published the research: healthy cynomolgus monkeysNonclinical Pharmacokinetics, Pharmacodynamics, and Translational Model of RO7297089, A Novel Anti-BCMA/CD16A Bispecific Tetravalent Antibody for the Treatment of Multiple Myeloma, in the Journal: (JOURNAL)
- what: This study characterized nonclinical pharmacokinetics (PK) pharmacodynamics (PD) soluble BCMA (sBCMA) and soluble CD16 (sCD16) changes following administration of RO7297089 to support clinical trials. Based on model simulations the authors propose more frequent dosing of RO7297089 compared to regular monthly frequency in . . .
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